Within the 12 seasons of Grey’s Anatomy, only four characters have remained or stayed alive since season one, who are…

Ellen Pompeo as Meredith Grey

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Justin Chambers as Alex Karev

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Chandra Wilson as Miranda Bailey

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James Pickens Jr. as Richard Webber

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Other known Grey's Anatomy characters:

Patrick Dempsey as Derek Shepherd

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Sandra Oh as Cristina Yang

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Sara Ramirez as Callie Torres

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Kevin McKidd as Owen Hunt

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Jesse Williams as Jackson Avery

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Sara Drew as April Kepner

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